Why Enzymes Are the Future of Exfoliation & Antioxidant Skincare
As AHA-free and acid-free skincare gain traction, enzymes offer clinical efficacy without irritation. Flychem’s EnzoGuard™ enzyme line is:
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Certified vegan
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High-activity: SOD 100,000 U/g | Bromelain 2400 GDU/g | Papain 900 TU/mg
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Designed for skin barrier safety, pH stability, and easy inclusion in emulsions or mists
EnzoGuard™ Product Portfolio
INCI |
Brand Name |
Activity Level |
Core Function |
Superoxide Dismutase |
100,000 U/g |
Antioxidant + anti-aging |
|
Bromelain |
2400 GDU/g |
Enzymatic exfoliation + calming |
|
Papain |
900 TU/mg |
Keratolytic exfoliation + glow |
All three are biofermented and non-animal-derived.
Use-Case Mapping for Skincare Formulators
Format |
Recommended Enzyme |
Use Level |
Skin Benefit |
Enzyme Cleanser |
CP or AC |
0.1–0.5% |
Gentle exfoliation |
Antioxidant Serum |
SOD |
0.01–0.1% |
Free radical protection |
Scalp Serum |
CP or AC |
0.05–0.2% |
Root buildup + sebum control |
Barrier Soothing Mask |
SOD + AC |
0.05–0.1% |
Post-acid calming + renewal |
Tolerability & Skin Safety Advantage
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Enzymes operate at neutral skin pH (5.0–6.2)
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No burning, flaking, or barrier damage
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Clinically safer than AHAs for sensitive and rosacea-prone skin
Ideal for:
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Post-procedure systems
- Sensitive skin lines
- K-beauty peels like AHA, BHA & PHA’s
Formulation SOP (Flychem Enzyme Inclusion)
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Add below 45°C (cool-down phase)
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Avoid strong oxidizers or alcohol-heavy systems
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Ideal pH: 5.0–6.5 for optimal activity
- Pre-hydrate lyophilized powder in water or glycerin
Why B2B Brands Choose EnzoGuard™ by Flychem
Feature |
EnzoGuard™ Advantage |
Yes (All three enzymes) |
|
High activity stability |
Yes – assay guaranteed |
Documentation pack |
Full global export-ready |
Application support |
Yes – SOPs, dispersion guidance, pH maps |
Global warehousing |
Yes – 3 Flychem hubs |
MOQ |
10g sample, 100g pilot, 1kg production |
Proteolytic enzymes like papain, bromelain, and ficin have garnered attention for their potential as natural exfoliating agents in skincare formulations. A comprehensive review published in the Journal of Cosmetic Dermatology explores their efficacy and applications in cosmetic products.
These enzymes are valued for their ability to gently remove dead skin cells, promoting a smoother and more radiant complexion. Their incorporation into skincare routines offers a natural alternative to synthetic exfoliants, aligning with the growing consumer demand for clean and plant-based beauty solutions.
ROI Calculator: Why Brands Switch to EnzoGuard™
Metric |
Result |
Enzyme cost per 30ml serum |
$0.12 (at 0.1% use) |
Typical retail uplift |
+$18–25 for enzyme-labeled serums |
Repurchase rate increase |
72–85% (enzyme vs. AHA category) |
Time to ROI |
~90 days for the first commercial batch |
Enzyme-labeled skincare now sees a 2.8× shelf pull rate in D2C brands.
Case Study: Flychem EnzoGuard™ in Enzyme Mist Toner (Japan)
- Challenge: Replace glycolic acid in sensitive skin exfoliation toner
- Solution: EnzoGuard™ CP at 0.3% + AC at 0.1% in dual-phase spray
Result:
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91% user-reported skin softness improvement in 14 days
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0 reports of redness or tingling
- 200,000 units sold across 4 D2C platforms
- Formulated with Flychem guidance, SOP, and validated activity report.
Global Regulatory Status
Region |
Status |
Documents Provided |
USA (MoCRA) |
✅ Cosmetic-safe |
COA, SDS, BSE-free cert |
EU (REACH) |
✅ Approved |
Activity + INCI cert |
India (BIS) |
✅ Non-listed exemption |
Vegan + assay reports |
China (IECIC) |
✅ All listed |
Export dossier ready |
Superoxide dismutase (SOD) is gaining recognition in the cosmetic industry for its potent antioxidant properties, offering protection against oxidative stress and contributing to skin health. A comprehensive review published in Antioxidants (Basel, Switzerland) delves into the diverse applications and underlying mechanisms of SOD in medicine, food, and cosmetics. SOD can mitigate damage from reactive oxygen species, thereby playing a crucial role in anti-aging skincare formulations. Its incorporation into cosmetic products underscores the shift towards bioactive ingredients that support skin resilience and vitality.
Frequently Asked Questions – Flychem EnzoGuard™
Q1: Are these enzymes synthetic or natural?
EnzoGuard™ enzymes are biofermented, vegan, and free of animal inputs.
Q2: Can I replace AHA with CP or AC?
Yes. EnzoGuard™ AC (bromelain) and CP (papain) exfoliate without irritation.
Q3: Are these enzymes stable in clear formulations?
Yes—when used under pH 6.0 and stored away from light + heat.
Q4: What is the MOQ?
Samples: 10g | Pilot: 100g | Production: 1kg minimum
Q5: How quickly can I get samples?
Within 48 hours from India or 3–5 days globally.
Q6: Do you provide formulation consultation?
Yes. Every sample kit includes a 1:1 call with Flychem’s chemists.
Final Step: Start Your Enzyme SKU with Flychem
Sample Kit Includes:
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EnzoGuard™ SOD / AC / CP (10g each)
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COA, SDS, activity certs, assay data
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SOP guide, regulatory sheet
- Formulation consultation session